Pharmacogenetic Testing

Genetic Testing Can Help Identify Your Risk for Medication Side Effects or Non-Response to Medications

Pharmacogenetic Testing analyzes how your genes guide the metabolism of prescription and over-the-counter (OTC) medications.

Pharmacogenetics is the study of an individual’s genetic variations in the body that are associated with an individual’s ability to metabolize prescription or over-the-counter drugs. pharmacogenetics was a natural outgrowth of human genome sequencing back in 2001. Medical research shows that individuals react differently to medications, due to their unique DNA. Pharmacogenetics, also referred to as “PGx” examines how a patient metabolizes specific drugs as encoded by their DNA. PGx testing reveals variations in drug metabolism genes that either encode less efficiently (defined as “poor metabolizers”) or more efficiently in terms of metabolic enzyme activity (defined as “rapid metabolizers”).

Identifying how a patient metabolizes a medication allows for prescribers to design a personalized treatment plan with medications that work best and are safest for that patient. In addition to reducing adverse drug reactions, PGx testing also increases patient confidence and medication adherence, decreases medical costs, and outlines optimal dosage of medications for that patient.

The Rxight® Pharmacogenetic Test is Available at Our Pharmacy

Rxight® was developed by MD Labs, a leading CLIA certified laboratory that specializes in pharmacogenetic testing. Rxight® is a pharmacogenetic testing program that is accurate, prompt, reliable, and easy to understand for pharmacists, prescribers and patients. MD Labs utilizes advanced technology to test for 60 alleles on 21 genes to see how a patient metabolizes over 200 medications.

The Rxight® pharmacogenetic test guides healthcare providers to take a course of action to help prevent severe drug side effects and allows for a more tailored drug treatment plan for patients

Rxight® was designed to be a key component for precision medicine. Precision medicine allows your healthcare provider and your pharmacist to work together to create a medication treatment plan that minimizes harmful drug reactions and helps the patient get on the right medications sooner.

With Rxight®, prescribers are able to understand how a patient’s genes affect the medications they prescribe. This allows the prescriber to make a more informed prescribing decision, rather than finding the right medication with the traditional trial-and-error approach, which can be frustrating, costly and dangerous.

The Rxight® pharmacogenetics test, which requires a simple cheek swab at our pharmacy, is designed to examine how your DNA guides the metabolism of over 200 clinically relevant prescription and over-the-counter medications (see list below). Some of these medications are commonly prescribed for diseases such as ADHD, diabetes, depression, or cancer.

Personalized Medication Review®

Your Rxight® report results will be reviewed with you in detail by a pharmacist trained in pharmacogenetics. With this information, you, your prescriber and your pharmacist can work together to create a treatment plan that is best for you, based on your specific genetic profile. Your results hold true for life because your genes do not change.

Knowing how you metabolize and respond to certain medications can help you avoid serious medication side effects before you begin treatment. Your results serve as your Medication Blueprint ™ based on your unique genetic makeup that shows you which medications might be harmful for you and which should work as intended. In this way, Rxight® gives you a good starting point from which to work and can help guide medication therapy in the present and future.

Over 200 Commonly Prescribed Medications Spanning 50+ Therapeutic Drug Classes are Analyzed

The following is a list of medications tested in the Rxight® panel across dozens of pharmacological classes. Click on a medication name to view a comprehensive article on the side effects from the drug or drug class. The articles were written by experts with degrees in medicine and genetics to ensure clinical integrity. We invite you to share this information with a pharmacist or your prescriber.

SPECIALTYDRUG CLASSGENERICBRAND
Anti-AddictiveOpiate AntagonistsBuprenorphineSubutex, Butrans, Buprenex
Anti-AddictiveNicotine Dependence MedicationsBupropionWellbutrin, Zyban, Aplenzin, Contrave
Anti-AddictiveOpiate AntagonistsNaltrexoneDepade, Revia, Vivitrol
Anti-FungalAntifungal MedicationsVoriconazoleVfend
CardiologyAntihypertensive AgentsIrbesartanAvapro
CardiologyAntihypertensive AgentsLosartanCozaar
CardiologyStatinsRosuvastatinCrestor
CardiologyBeta BlockersPropranololInderal, InnoPran, Hemangeol
CardiologyStatinsAtorvastatinLipitor
CardiologyAntiplateletsClopidogrelPlavix
CardiologyDirect Thrombin InhibitorsDabigatran-EtexilatePradaxa
CardiologyAntianginal MedicationsRanolazineRanexa
CardiologyAntiarrhytmicsPropafenoneRythmol
CardiologyAnticoagulantsWarfarinCoumadin, Jantoven
CardiologyAnticoagulantsRivaroxabanXarelto
CardiologyStatinsSimvastatinZocor
CardiologyAnticoagulantsApixabanEliquis
CardiologyAntihypertensive AgentsAzilsartan KamedoxomilEdarbi
CardiologyBeta BlockersCarvedilolCoreg
CardiologyAntihypertensive AgentsDoxazosinCardura, Doxadura
CardiologyAntiarrhytmicsFlecainideTambocor
CardiologyStatinsFluvastatinLescol
CardiologyAnticoagulantsFondaparinuxArixtra
CardiologyBeta BlockersLabetalolNormodyne, Trandate
CardiologyStatinsLovastatinMevacor, Altocor, Altoprev
CardiologyBeta BlockersMetoprololLopressor, Toprol
CardiologyAntiarrhytmicsMexiletineMexitil
CardiologyBeta BlockersNebivololBystolic
CardiologyStatinsPitavastatinLivalo
CardiologyAntiplateletsPrasugrelEffient
CardiologyStatinsPravastatinPravachol
CardiologyAntiplateletsTicagrelorBrilinta
CardiologyBeta BlockersTimololBlocadren, Timoptic
CardiologyDiureticsTorsemideDemadex
CardiologyAntiplateletsVorapaxarZontivity
DiabetesSulfonylureasGlimepirideAmaryl
DiabetesSulfonylureasGlipizideGlucotrol
DiabetesSulfonylureasChlorpropamideDiabenese
DiabetesBiguanidesGlyburideDiaBeta, Micronase, Glynase
DiabetesMeglitinidesNateglinideStarlix
DiabetesThiazolidinedionesPioglitazoneActos
DiabetesMeglitinidesRepaglinidePrandin
DiabetesThiazolidinedionesRosiglitazoneAvandia
DiabetesSulfonylureasTolbutamideOrinase, Tol-Tab
EndocrinologyThyroid HormonesLevothyroxineSynthroid, Tirosint, Unithroid, Levothroid, Levoxyl, Novothyrox
GastroenterologyProton Pump InhibitorsEsomeprazoleNexium
GastroenterologyProkineticsMetoclopramideReglan, Maxolon, Metozolv
GastroenterologyProton Pump InhibitorsDexlansoprazoleDexilant, Kapidex
Gastroenterology5-HT3 Receptor AntagonistsDolasetronAnzemet
GastroenterologyProton Pump InhibitorsLansoprazolePrevacid
GastroenterologyProton Pump InhibitorsOmeprazolePrilosec
Gastroenterology5-HT3 Receptor AntagonistsOndansetronZofran, Zuplenz
Gastroenterology5-HT3 Receptor AntagonistsPalonosetronAloxi
GastroenterologyProton Pump InhibitorsPantoprazoleProtonix
GastroenterologyProton Pump InhibitorsRabeprazoleAciphex
ImmunosupportiveImmunosuppressantsAzathioprineAzasan, Imuran
ImmunosupportiveImmunosuppressantsTacrolimusPrograf, Hecoria, Astagraf
Infectious DiseaseAntimalarialsProguanilPaludrine
NeurologyMuscle RelaxantsCyclobenzaprineFlexeril, Amrix, Fexmid
NeurologyAnticonvulsantsGabapentinNeurontin, Gralise, Gabarone, Fanatrex
NeurologyAnticonvulsantsCarbamazepineTegretol, Carbatrol, Epitol
NeurologyMuscle RelaxantsCarisoprodolSoma, Vanadom
NeurologyAntimuscarinicsDarifenacinEnablex
NeurologyAnticonvulsantsEslicarbazepine-AcetateAptiom
NeurologyAnticonvulsantsEthosuximideZarontin
NeurologyAnticonvulsantsEzogabinePotiga
NeurologyAnticonvulsantsFelbamateFelbatol
NeurologyAntimuscarinicsFesoterodineToviaz
NeurologyAnticonvulsantsFosphenytoinCerebyx
NeurologyAnticonvulsantsLacosamideVimpat
NeurologyAnticonvulsantsLamotrigineLamictal
NeurologyAnticonvulsantsLevetiracetamKeppra, Elepsia
NeurologyMuscle RelaxantsMetaxaloneSkelaxin
NeurologyMuscle RelaxantsMethocarbamolRobaxin, Carbacot, Skelex
NeurologyBeta BlockersMirabegronMyrbetriq
NeurologyAnticonvulsantsOxcarbazepineTrileptal, Oxtellar
NeurologyAntispasmodicsOxybutyninDitropan
NeurologyAnticonvulsantsPerampanelFycompa
NeurologyAnticonvulsantsPhenobarbitalLuminal, Solfoton
NeurologyAnticonvulsantsPhenytoinDilantin, Phenytoin Sodium, Phenytek
NeurologyAnticonvulsantsPregabalinLyrica
NeurologyAnticonvulsantsPrimidoneMysoline
NeurologyAnticonvulsantsRufinamideBanzel
NeurologyAntimuscarinicsSolifenacinVesicare
NeurologyAnticonvulsantsTiagabineGabitril
NeurologyCholinergic AgonistsTolterodineDetrol
NeurologyAnticonvulsantsTopiramateTopamax, Topiragen, Qudexy
NeurologyAntimuscarinicsTrospiumSanctura
NeurologyAnticonvulsantsValproic-AcidDepakote, Depakene, Stavzor
NeurologyAnticonvulsantsVigabatrinSabril
NeurologyAnticonvulsantsZonisamideZonegran
OncologyAntimetabolitesFluorouracilAdrucil, Carac, Efudex, Fluoroplex
OncologyAntimetabolitesCapecitabineXeloda
OncologyPurine AntagonistsMercaptopurinePurinethol, Purixan
OncologyAntimetabolitesMethotrexateOtrexup, Rasuvo, Trexall
OncologyTaxanesPaclitaxelOnxol, Abraxane, Taxol
OncologyAntimetabolitesThioguanineTabloid
OncologySignal Transduction InhibitorsGefitinibIressa
OthersGlucosylceramide Synthase InhibitorsEliglustatCerdelga
OthersCholinergic AgonistsCevimelineEvoxac
Pain ManagementOpioidsAlfentanilAlfenta
Pain ManagementNSAIDsDiclofenacVoltaren, Zorvolex, Cataflam, Cambia
Pain ManagementNSAIDsCelecoxibCelebrex
Pain ManagementOpioidsCodeineFioricet w/Codeine, Robitussin-AC, Tylenol 1,2,3,4
Pain ManagementOpioidsMorphineMS Contin, Kadian, Roxanol
Pain ManagementOpioidsTramadolUltram, ConZip, Ryzolt
Pain ManagementOpioidsHydrocodoneHysingla, Lorcet, Norco, Vicodin
Pain ManagementOpioidsDihydrocodeineSynalgos-DC, Trezix, Zerlor, Panlor
Pain ManagementOpioidsFentanylDuragesic, Subsys, Actiq
Pain ManagementNSAIDsFlurbiprofenAnsaid
Pain ManagementOpioidsHydromorphoneDilaudid, Exalgo
Pain ManagementNSAIDsIbuprofenAdvil, Motrin
Pain ManagementNSAIDsIndomethacinIndocin, Tivorbex
Pain ManagementNSAIDsKetoprofenOrudis, Actron, Oruvail, Nexcede
Pain ManagementNSAIDsKetorolacToradol, Sprix
Pain ManagementOpioidsLevorphanolLevo Dromoran
Pain ManagementNSAIDsMeloxicamMobic
Pain ManagementOpioidsMeperidineDemerol, Meperitab
Pain ManagementOpioidsMethadoneDolophine, Methadose
Pain ManagementSNRIsMilnacipranSavella
Pain ManagementNSAIDsNabumetoneRelafen
Pain ManagementNSAIDsNaproxenAleve, Naprosyn, Anaprox
Pain ManagementOpioidsOxycodonePercocet, Oxycontin
Pain ManagementOpioidsOxymorphoneOpana, Numorphan
Pain ManagementNSAIDsPiroxicamFeldene
Pain ManagementOpioidsSufentanilSufenta
Pain ManagementNSAIDsSulindacClinoril
Pain ManagementOpioidsTapentadolNucynta
Psychiatry/Behavioral HealthAntipsychoticsAripiprazoleAbilify, Maintena
Psychiatry/Behavioral HealthADHD MedicationsAmphetamine Adderall
Psychiatry/Behavioral HealthAnticonvulsantsBrivaracetamBriviact
Psychiatry/Behavioral HealthAntipsychoticsClozapineClozaril, FazaClo, Zaponex
Psychiatry/Behavioral HealthSNRIsDuloxetineCymbalta
Psychiatry/Behavioral HealthTricyclic AntidepressantsAmitriptylineElavil, Endep, Vanatrip
Psychiatry/Behavioral HealthADHD MedicationsDexmethylphenidateFocalin
Psychiatry/Behavioral HealthAntipsychoticsHaloperidolHaldol
Psychiatry/Behavioral HealthSSRIsEscitalopramLexapro
Psychiatry/Behavioral HealthSNRIsDesvenlafaxinePristiq, Khedezla
Psychiatry/Behavioral HealthSSRIsFluoxetineProzac, Sarafem, Rapiflux
Psychiatry/Behavioral HealthAntipsychoticsAsenapineSaphris
Psychiatry/Behavioral HealthAntianxiety MedicationsDiazepamValium, Diastat
Psychiatry/Behavioral HealthAntianxiety MedicationsAlprazolamXanax, Niravam
Psychiatry/Behavioral HealthTricyclic AntidepressantsAmoxapineAsendin
Psychiatry/Behavioral HealthADHD MedicationsAtomoxetineStrattera
Psychiatry/Behavioral HealthAntipsychoticsBrexpiprazoleRexulti
Psychiatry/Behavioral HealthAntipsychoticsChlorpromazineThorazine, Ormazine
Psychiatry/Behavioral HealthSSRIsCitalopramCelexa
Psychiatry/Behavioral HealthAntianxiety MedicationsClobazamOnfi
Psychiatry/Behavioral HealthTricyclic AntidepressantsClomipramineAnafranil
Psychiatry/Behavioral HealthAntianxiety MedicationsClonazepamKlonopin
Psychiatry/Behavioral HealthAntianxiety MedicationsClonidineKapvay
Psychiatry/Behavioral HealthTricyclic AntidepressantsDesipramineNorpramin
Psychiatry/Behavioral HealthADHD MedicationsDextroamphetamineDexedrine, Dextrostat, ProCentra
Psychiatry/Behavioral HealthAlzheimer's TreatmentsDonepezilAricept
Psychiatry/Behavioral HealthTricyclic AntidepressantsDoxepinSilenor, Sinequan, Adapin
Psychiatry/Behavioral HealthAntianxiety MedicationsFluphenazineProlixin, Permitil
Psychiatry/Behavioral HealthAntipsychoticsFluvoxamineLuvox
Psychiatry/Behavioral HealthAlzheimer's TreatmentsGalantamineRazadyne
Psychiatry/Behavioral HealthAntipsychoticsIloperidoneFanapt
Psychiatry/Behavioral HealthTricyclic AntidepressantsImipramineTofranil
Psychiatry/Behavioral HealthSNRIsLevomilnacipranFetzima
Psychiatry/Behavioral HealthADHD MedicationsLisdexamfetamineVyvanse
Psychiatry/Behavioral HealthAntianxiety MedicationsLorazepamAtivan
Psychiatry/Behavioral HealthAntipsychoticsLurasidoneLatuda
Psychiatry/Behavioral HealthTetracyclic AntidepressantsMaprotilineLudiomil
Psychiatry/Behavioral HealthAlzheimer's TreatmentsMemantineNamenda
Psychiatry/Behavioral HealthADHD MedicationsMethylphenidateConcerta, Ritalin, Quillivant
Psychiatry/Behavioral HealthTetracyclic AntidepressantsMirtazapineRemeron
Psychiatry/Behavioral HealthSNRIsNefazodoneSerzone
Psychiatry/Behavioral HealthTricyclic AntidepressantsNortriptylinePamelor, Aventyl Hydrochloride
Psychiatry/Behavioral HealthAntipsychoticsOlanzapineZyprexa
Psychiatry/Behavioral HealthAntianxiety MedicationsOxazepamSerax
Psychiatry/Behavioral HealthAntipsychoticsPaliperidoneInvega
Psychiatry/Behavioral HealthSSRIsParoxetinePaxil, Brisdelle, Pexeva
Psychiatry/Behavioral HealthAntipsychoticsPerphenazineTrilafon
Psychiatry/Behavioral HealthAntipsychoticsPimozideOrap
Psychiatry/Behavioral HealthTricyclic AntidepressantsProtriptylineVivactil
Psychiatry/Behavioral HealthAntipsychoticsQuetiapineSeroquel
Psychiatry/Behavioral HealthAntipsychoticsRisperidoneRisperdal
Psychiatry/Behavioral HealthSSRIsSertralineZoloft
Psychiatry/Behavioral HealthMonoamine DepleterTetrabenazineXenazine
Psychiatry/Behavioral HealthAntipsychoticsThioridazineMellaril
Psychiatry/Behavioral HealthAntipsychoticsThiothixeneNavane
Psychiatry/Behavioral HealthSARIsTrazodoneOleptro
Psychiatry/Behavioral HealthAntipsychoticsTrifluoperazineStelazine
Psychiatry/Behavioral HealthTricyclic AntidepressantsTrimipramineSurmontil
Psychiatry/Behavioral HealthSNRIsVenlafaxineEffexor
Psychiatry/Behavioral HealthSSRIsVilazodoneViibryd
Psychiatry/Behavioral HealthSerotonin ModulatorsVortioxetineBrintellix
Psychiatry/Behavioral HealthAntipsychoticsZiprasidoneGeodon
RespiratoryMorphinanDextromethorphanDelsym, DexAlone
RheumatologyPDE4 InhibitorsApremilastOtezla
RheumatologyDMARDsLeflunomideArava
RheumatologyJAK InhibitorsTofacitinibXeljanz
UrologyAntiandrogensDutasterideAvodart
UrologyErectile Dysfunction MedicationsTadalafilCialis, Adcirca
UrologyAlpha BlockersTamsulosinFlomax
UrologyAntiandrogensFinasterideProscar,Propecia
UrologyAlpha BlockersAlfuzosinUroXatral
UrologyErectile Dysfunction MedicationsAvanafilStendra
UrologyErectile Dysfunction MedicationsSildenafilViagra, Revatio
UrologyAlpha BlockersSilodosinRapaflo
UrologyAlpha BlockersTerazosinHytrin
UrologyErectile Dysfunction MedicationsVardenafilLevitra, Staxyn